Unlike many other drugs that treat viruses, Sovaldi does not suppress hepatitis C, a virus that kills roughly 250,000 people around the world each year. It cures it.
“Normally you have a virus, and your body fights it off or your body fights it to a standstill and you just have it forever, basically, and hope it remains dormant more or less,” Laufer said. “The holy grail for every virologist is to find a way to drain the viral reservoir, and Sovaldi does this. You take one pill of Sovaldi a day for 12 weeks and then you don’t have hepatitis C anymore.”
The problem is that those pills are under patent, and they cost $1,000 per pill.
“Literally, if you have $84,000 then hepatitis C is not your problem anymore,” Laufer said. “But given that there are other methodologies for managing hepatitis C that are not curing it and that are cheaper, insurance typically will not cover [Sovaldi]. And so we’ve got this incredible technology and it’s sitting on the shelf except for people who are ridiculously wealthy.”
So Four Thieves Vinegar Collective set out to teach people how to make their own version of Sovaldi. Chemists at the collective thought the DIY version would cost about $300 for the entire course of medication, or about $3.57 per pill. But they were wrong.
“It’s actually just a little under $70 (83 cents per pill), which just kind of blew my mind when they finally showed me the results,” Laufer said. “I was like, can we do the math here again?”
So, the laws should be changed and every pharma exec, board members and so on who prices like this should be locked up for life.
Next, all laws need to be changed to end the doctrine that only profit maximization for shareholders matters.
Third, pharma needs to move a bounty system. According to WHO there are 58 million people with Hep C around the world. Put up a bounty of 1,000 times that: 58 billion, for a cure, minus the cost per cure. Research costs can also be added to the bounty, once the cure is certified, not before. A consortium of rich governments can create the bounty funds, with poorer countries allowed in for free. A UN org reporting only to the general assembly should probably administer it.
Fourth, end pharma patents. All of them. All information, including manufacturing information is shared.
Fifth: for all palliatives, profits must be capped at 5% max.
Sixth: move most research to government and non-profits. Real non-profits, none of the Chat-GPT nonsense.
Seventh: remove further monetary incentives to just research forever: everyone involved is capped at a salary of 2xmedian income in the G-20 or something similar. You want the big pay off? You have to actually cure the disease.
Eighth: Force scientists and technicians to be “in on the bounty.” Some sort of fairly even split between people who worked on the cure.
There are other actions which should be taken, but these are the basics. Right now we aren’t curing people we can, and companies prefer palliatives to cures because they can charge until the person dies. We need to emphasize cures and make sure no one gets rich selling palliatives.
In the meantime the right to make your own medicines needs to be 100% legal and supported.
For those advising an attempt to take over the Republican Party. I think candidly that that is even less likely than taking over the Democratic Party.
I live in, and am involved in local politics and environmental activism in, a region that, despite being in a very Blue State, is quite conservative, with some of the towns around here reliably voting for GOP candidates — in Massachusetts — at rates above 60 and 70% (other towns are more reliably Democratic, these differences are fascinating at a sociological level, and quite complicated).
I am in coalition with these conservatives on a critical important local issue where 90 percent of the populace agrees that a corporation is lawless and must be stopped. I grew up with some of them, and know them well, we are of the same small communities (this is also true of the liberals, the left, the non-engaged, the right-wing and left-wing online street fighters, many more — these are smaller towns for Massachusetts, with one exception).
Despite this coalition, or rather because of it, and dealing with them, I think it’s unlikely they are going to be a good candidate for entryism. For one thing, they are viscerally and often just off the wall in their hardcore anti-Communism and 1950s-era redbaiting.
The other thing is that they have as kind of their Ur-Principle the idea that Private Property Is Sacred (this is, as Ur-Principles so often are, is frequently and seemingly without dissonance contradicted by them in the actual practice of their lives). They do not distinguish between the person owning a small cottage and Elon Musk; for them, private property is private property.
A third factor is that fifty years of talk radio, cable news, and now Facebook and other social media have marinated them in a culture of querulous suspicion and anti-reason; they fall for just lunatic conspiracy stuff, and while some of them are just naturally intelligent enough that they fight through this and make real contributions to our local governments, it’s still their native idiom, if that makes sense (like, believing basically every election is stolen; despite the minimizing of certain interlocutors of Trump’s misdeeds, this is a real one, this baseless accusation of fraudulent or stolen elections — this is a corrosive rhetorical move, and one that makes the actual practical life of our bodies politic in the real world more difficult.
Nor is Russiagate apposite here; Russiagate was nonsense, but Hillary Clinton, of whom I am not a fan, did show up to Trump’s 2017 Inauguration; she did acknowledge the vote totals were correct, and that she legitimately lost in the electoral college; this is _categorically_ different than Trump’s conduct in 2020-21).
A fourth factor: they genuinely dislike Difference and a pluralistic and open society; many of them are openly bigoted towards LGBTQ people. We had a Klan presence here in southeastern Massachusetts into the 1950s, and that impulse didn’t just go away. Indeed, my own Town’s High School, from which I graduated 20+ years ago, had a significant problem with what can only be described as anti-Semitic and Nazi-sympathizing public behavior by the football team. We have the local evangelical holy rollers running for School Committee (in Plymouth, Mass.) talking about banning books, in just total disregard for the U.S. and Mass. Constitutions.
They are also obsessed with culture war nonsense. Just, like, obsessed.
The thing I should emphasize: the conservatives are often extremely intelligent, and will see any kind of entryist from a mile away. I should also note I actually quite like many of them at a personal level; I don’t think they are bad people (some are, but not most), just misguided and wrong on many issues (sometimes, they are right, and I take coalition with them where it presents itself; this is natural in the parliamentary environment of Town Meeting societies).
Finally, Republicans have their own Machine which is even worse than the Democratic Machine, which at least has to pretend to some notion of human well-being. The GOP Machine in my experience down here are connected to local business elites and are also canny, and just like, wildly amoral, and won’t give up the party without a fight.
So, taken together, and played out across the country, I think it will be extremely difficult to engage in any kind of Left entryist strategy in the Republican Party.
My own strategy is premised on local politics — I live in a directly democratic Town Meeting form of government, and if I want to write a statute for the Town, I can get myself and nine other inhabitants of the Town together and put it before the Annual Town Meeting. That’s a lot of power, so I exercise what power I am able to in order to advance the goals of the Commonwealth thought that guided the authors of the Massachusetts Constitution, and, at a larger level, the American Revolution.