The horizon is not so far as we can see, but as far as we can imagine

Author: Ian Welsh Page 24 of 406

Pharma Charges 80K to cure Hepatitis C. The Manufacturing Cost is $78

Yeah.

Unlike many other drugs that treat viruses, Sovaldi does not suppress hepatitis C, a virus that kills roughly 250,000 people around the world each year. It cures it.

“Normally you have a virus, and your body fights it off or your body fights it to a standstill and you just have it forever, basically, and hope it remains dormant more or less,” Laufer said. “The holy grail for every virologist is to find a way to drain the viral reservoir, and Sovaldi does this. You take one pill of Sovaldi a day for 12 weeks and then you don’t have hepatitis C anymore.”

The problem is that those pills are under patent, and they cost $1,000 per pill.

“Literally, if you have $84,000 then hepatitis C is not your problem anymore,” Laufer said. “But given that there are other methodologies for managing hepatitis C that are not curing it and that are cheaper, insurance typically will not cover [Sovaldi]. And so we’ve got this incredible technology and it’s sitting on the shelf except for people who are ridiculously wealthy.”

So Four Thieves Vinegar Collective set out to teach people how to make their own version of Sovaldi. Chemists at the collective thought the DIY version would cost about $300 for the entire course of medication, or about $3.57 per pill. But they were wrong.

“It’s actually just a little under $70 (83 cents per pill), which just kind of blew my mind when they finally showed me the results,” Laufer said. “I was like, can we do the math here again?”

So, the laws should be changed and every pharma exec, board members and so on who prices like this should be locked up for life.

Next, all laws need to be changed to end the doctrine that only profit maximization for shareholders matters.

Third, pharma needs to move a bounty system. According to WHO there are 58 million people with Hep C around the world. Put up a bounty of 1,000 times that: 58 billion, for a cure, minus the cost per cure. Research costs can also be added to the bounty, once the cure is certified, not before. A consortium of rich governments can create the bounty funds, with poorer countries allowed in for free. A UN org reporting only to the general assembly should probably administer it.

Fourth, end pharma patents. All of them. All information, including manufacturing information is shared.

Fifth: for all palliatives, profits must be capped at 5% max.

Sixth: move most research to government and non-profits. Real non-profits, none of the Chat-GPT nonsense.

Seventh: remove further monetary incentives to just research forever: everyone involved is capped at a salary of 2xmedian income in the G-20 or something similar. You want the big pay off? You have to actually cure the disease.

Eighth: Force scientists and technicians to be “in on the bounty.” Some sort of fairly even split between people who worked on the cure.

There are other actions which should be taken, but these are the basics. Right now we aren’t curing people we can, and companies prefer palliatives to cures because they can charge until the person dies. We need to emphasize cures and make sure no one gets rich selling palliatives.

In the meantime the right to make your own medicines needs to be 100% legal and supported.


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Why The Left Taking Over The Republican Party Is Even Harder Than Taking Over The Democratic Party

By Swamp Yankee

(Ian–this is another elevated comment. I thought (and think) it’s an excellent one, informed by life experience. In general the quality of comments lately has impressed me.)

For those advising an attempt to take over the Republican Party. I think candidly that that is even less likely than taking over the Democratic Party.

I live in, and am involved in local politics and environmental activism in, a region that, despite being in a very Blue State, is quite conservative, with some of the towns around here reliably voting for GOP candidates — in Massachusetts — at rates above 60 and 70% (other towns are more reliably Democratic, these differences are fascinating at a sociological level, and quite complicated).

I am in coalition with these conservatives on a critical important local issue where 90 percent of the populace agrees that a corporation is lawless and must be stopped. I grew up with some of them, and know them well, we are of the same small communities (this is also true of the liberals, the left, the non-engaged, the right-wing and left-wing online street fighters, many more — these are smaller towns for Massachusetts, with one exception).

Despite this coalition, or rather because of it, and dealing with them, I think it’s unlikely they are going to be a good candidate for entryism. For one thing, they are viscerally and often just off the wall in their hardcore anti-Communism and 1950s-era redbaiting.

The other thing is that they have as kind of their Ur-Principle the idea that Private Property Is Sacred (this is, as Ur-Principles so often are, is frequently and seemingly without dissonance contradicted by them in the actual practice of their lives). They do not distinguish between the person owning a small cottage and Elon Musk; for them, private property is private property.

A third factor is that fifty years of talk radio, cable news, and now Facebook and other social media have marinated them in a culture of querulous suspicion and anti-reason; they fall for just lunatic conspiracy stuff, and while some of them are just naturally intelligent enough that they fight through this and make real contributions to our local governments, it’s still their native idiom, if that makes sense (like, believing basically every election is stolen; despite the minimizing of certain interlocutors of Trump’s misdeeds, this is a real one, this baseless accusation of fraudulent or stolen elections — this is a corrosive rhetorical move, and one that makes the actual practical life of our bodies politic in the real world more difficult.
Nor is Russiagate apposite here; Russiagate was nonsense, but Hillary Clinton, of whom I am not a fan, did show up to Trump’s 2017 Inauguration; she did acknowledge the vote totals were correct, and that she legitimately lost in the electoral college; this is _categorically_ different than Trump’s conduct in 2020-21).

A fourth factor: they genuinely dislike Difference and a pluralistic and open society; many of them are openly bigoted towards LGBTQ people. We had a Klan presence here in southeastern Massachusetts into the 1950s, and that impulse didn’t just go away. Indeed, my own Town’s High School, from which I graduated 20+ years ago, had a significant problem with what can only be described as anti-Semitic and Nazi-sympathizing public behavior by the football team. We have the local evangelical holy rollers running for School Committee (in Plymouth, Mass.) talking about banning books, in just total disregard for the U.S. and Mass. Constitutions.

They are also obsessed with culture war nonsense. Just, like, obsessed.

The thing I should emphasize: the conservatives are often extremely intelligent, and will see any kind of entryist from a mile away. I should also note I actually quite like many of them at a personal level; I don’t think they are bad people (some are, but not most), just misguided and wrong on many issues (sometimes, they are right, and I take coalition with them where it presents itself; this is natural in the parliamentary environment of Town Meeting societies).

Finally, Republicans have their own Machine which is even worse than the Democratic Machine, which at least has to pretend to some notion of human well-being. The GOP Machine in my experience down here are connected to local business elites and are also canny, and just like, wildly amoral, and won’t give up the party without a fight.

So, taken together, and played out across the country, I think it will be extremely difficult to engage in any kind of Left entryist strategy in the Republican Party.

My own strategy is premised on local politics — I live in a directly democratic Town Meeting form of government, and if I want to write a statute for the Town, I can get myself and nine other inhabitants of the Town together and put it before the Annual Town Meeting. That’s a lot of power, so I exercise what power I am able to in order to advance the goals of the Commonwealth thought that guided the authors of the Massachusetts Constitution, and, at a larger level, the American Revolution.

Types Of Civilization Collapse

We’ve had a couple posts recently on collapse. One, by Nate Wilcox, on the possibility of civil war and a another by commenter Grim Jim on just how many people would die in a civilization collapse.

Let’s take a look at the dimensions of collapse.

First is slow vs. fast. John Michael Greer tends to push slow, though his position is more nuanced than that. In the slow collapse things just keep getting shittier, with, perhaps, some break points. (If there’s a civil war, there’s a big jump in crap.) In this model it’s hard to say exactly when the collapse happens. When did the Western Roman Empire fall? There are easily half a dozen possible dates one could argue for, and that’s a collapse complete with a barbarian invasion.

In general expect countries which can feed and fuel themselves to be in the slow collapse bucket, though there’ll be exceptions, especially if they can’t defend themselves. Canada is one of those, if it isn’t invaded by America, which it probably will be. Russia is also in it, if they don’t wind up in a nuclear war.

Remember that modern agriculture will be affected by collapse: heavy use of fertilizer, pesticides and oils makes it vulnerable. So if a country appears to have a massive surplus, well, it may not. When AMOC ends and Europe loses ten degrees celcius overnight, they may as well.

The same here is true of water: when glaciers finish melting and most snow pack is gone, there’s going to be a lot less of it. So look at where the surplus food and water is coming from.

Second is distribution by time and place. Everyone likes to quote Gibson, “the future is already here, it’s just not evenly distributed.” Some countries have already collapsed. Sri Lanka, for example. Others are further along the path: in the first world, Britain’s a good example. Within countries some places collapse first: Northern England is notably a hole. Catholic Belfast has never not been poor, and so on.

In the US there are places where we can be sure of regional collapse—as Sean-Paul pointed out to me, the Texas triangle is just going to run out of water in a couple decades. The American Southwest is doomed for pretty much the same reason.

As for that, the homelessness epidemic shows that for many Americans, the collapse is already here.

Internationally Bangladesh will be one of the first high-population countries to collapse. Among major countries, India will be one of the first. The Europeans can go any time when the Atlantic Meridian Overturning Current (AMOC) ends: and that’s due sometime in the next 50 years, as a “when not if” proposition. I don’t know Africa well enough, but obviously multiple countries there are already close to collapse and the only thin which could put that off would be concerted efforts by China (financially and developmentally) and Russia (food and resource aid.)

China’s a hard one to predict: they have huge climate change vulnerabilities, especially to flooding in the North, heat in the North and water in general. On the other hand, if they play it smart they have the world’s industrial base and the best chance of adaptation and mitigation, especially due to their alliance with Russia, which will keep them in resources and food longer than otherwise. Since Russia mutually benefits, they’ll keep the Chinese topped up as a priority.

Which leads to the bigger point: when food starts getting scarce countries will stop exporting, and this is when food importing countries will start real collapse (and food riots, and civil war.)

As for water scarcity, that’s when you’ll get water wars.

And both will exacerbate any internal tensions. When there’s not enough to eat or drink, the “other” whoever that is, is likely to get it in the neck. Countries with significant internal rifts, like India between Hindus and Muslims/High and Low-Caste will see incredible violence and mass murder of minorities. Whether that also describes America is a question much debated, but at the least there will be a vast increase in discrimination and at the worst purges or even civil war.

In Europe there will be huge backlashes against visible minorities, especially Muslim ones and perhaps also Jews, as they are tarred with genocide and accusations of controlling governments.

I would suggest to expect a general pattern of slow decline punctuated by cliff-drops. Things will slowly get shittier, then suddenly get a lot shittier. To give a small example, in Ontario where I live, before Covid you could expect to be seen in an emergency department within a couple hours and to get an MRI or CT scan within a couple months, often a few weeks. Now it takes ten to twelve hours to be seen in an emergency (unless you’re obviously bleeding out or can’t breathe) and imaging tests can take six to nine months.

In collapse some foods (starting with imported ones) will go from widely available to just not on the shelf. Medicines which are imported will stop being available, again in slow decline then suddenly, almost impossible to find.

Slow, then precipitous, then slow, then precipitous.

The general prescription here, for small groups and individuals is to make yourself as independent of the grid as possible, to figure out how to grow climate controlled food, and to find a water source. Even in slow collapse models there will be large numbers of brownouts, water will be shitty if available (hello England) and so on. If you can’t handle at least a few hours or days off-grid, life will be miserable.

Collapse isn’t a disaster movie, though there are parts of it that are. (All the people made homeless by wildfires know this, and there will be coastal inundations). Rather it’s a series of long slide, punctuated by catastrophes


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Britain Is Arresting Prominent Pro-Palestinian Activists

For “supporting a proscribed organization”. Aka. Hamas. The arrests are by counter-terrorism police.

Sarah Wilkinson’s arrest:

The police came to her house just before 7.30am. 12 of them in total, some of them in plain clothes from the counter terrorism police. They said she was under arrest for “content that she has posted online.” Her house is being raided & they have seized all her electronic devices.

Others who have been arrested include Richard Barnard, Richard Medhurst and Craig Murray.

This is the law they are being charged under:

I have long opposed all “proscribed organization laws.” They destroy freedom of association and freedom of speech. In the US RICO is the primary culprit, justified by being used to go after the Mafia, but they’re all bad and they all wind up being misused. If someone commits an actual crime they should be charged, but freedom of association is fundamental and should not be abridged. RICO should be unconstitutional, but somehow isn’t. As for Britain, well, the laws on the books are draconian but were often not enforced.

Starmer, Britain’s PM, has always treated his job as crushing the left. This was clear when he was leader of the opposition and purged the party of the left, and now he’s done something even the Conservatives did not do, and done it to protect a genocide. When you look at the austerity politics his government is enforcing, it’s clear that he’s actually slightly worse than the Conservatives, which is quite the achievement. A monster in all regards.

In general the West, and especially Europe, is cracking down on freedom of speech. Strong, confident elites don’t need to do this. “Say what you want, it doesn’t matter” is how they think and feel, and they know it’s better to have people shooting off their mouths than acting.

But weak elites; scared elites; crack down.

A lot of this comes down “when times are good, people talk but rarely do.” In the best of times, most people fundamentally support the system. They want changes, yes, but they aren’t actually a threat to elites. But life in Britain has been getting worse for over forty years now and Corbyn scared the Labour establishment: he should never have been able to be elected leader and he should never have come within a hair of winning his first election.

So crush, crush away. Make examples of people.

The same is true of France’s arrest of the CEO of Telegram. This is all about instilling fear. Stay within the lines or we’ll crush you.


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Open Thread

Use to discuss topics unrelated to recent posts.

How Many Americans Will Die From Civilization Collapse?

These are elevated comments by GrimJim.

What’s useful about this is that the estimates are made explicit. — Ian

Eleven percent of Americans use insulin to survive. They are dead within three months of the power going out.

Between 17 and 20% of Americans need weekly if not daily mental health medication. They are all either dead or reduced to needing constant care within three to six months. (Ian-probably an overstatement, many will be functional once they come off, but a non-tapered withdrawal from most ant-depressants or GABA drugs is ugly.)

Altogether, some 66% of Americans take some kind of life-saving or life-supporting medication daily. Let’s say that at least half of those are dead within one year of the lights going out. That’s 33% of the population.

During the Rwandan Genocide, about 75% of the Tutsi population was killed in merely 100 days. Like Rwanda and unlike Bosnia, there will be no one trying to stop it, no outside forces intervening. Imagine the Pseudo-Christian White Nationalists killing 75% of the “undesirables” they can get their hands on. Imagine many more of those American “undesirables” being able to fight back as they are being genocided (the Tutsis died en masse, not generally have the resources to fight back). It will quickly become tit-for-tat, with no mercy on either side, as the “undesirables” will no longer grant any mercy once they figure out what the Pseudo-Christian White Nationalists plan for them. So that’s about 75% of 40% of the remaining population.

Then there will further be a much more massive death all around due to the lack of medical supplies and services. Add in pestilence and plague, and that increases the number.

And about a year in, the survivors will have used up remaining food stocks. If they have been unable to start farming, on a traditional MINIMAL level of about 5 to 10 farmers per 1 non-farmer, there will be starvation.

So…

345,000,000 Americans to start…
less 33% or 113,850,000 from medical issues = 231,150,000
less 75% of 40% (69,345,000) from Genocide = 161,805,000
less ~10% from plague and pestilence (16,180,500) = 145,624,500
And less ~20% due to starvation (29,124,900) = 116,499,600.

My estimate is that there will be only about 116,000,000 Americans left within two years of the collapse and the start of ACWII. That’s a 66% death rate within two years. That’s a minimum, with my being generous on all the numbers.

Estimates based on an EMP attack that takes down the entire USA power grid have been a 90% death rate in merely one year. So I’m actually looking at things with rose-colored glasses…

And Elevated Comment two (on farms and food)

Note: Right now only 2% of Americans live on farms.

TWO PERCENT.

And all those farms, with the exception of Amish and some Mennonite farms, depend on gasoline and machines. and most of those machines are modern, complex, computer-based machines, which will be useless within weeks or months of the economy collapsing.

During the Great Depression, 20% of Americans lived in farms. This is the only reason starvation was not rampant. Just about everyone was related to or knew someone who had a farm, so they could count on them for some support.

Now, almost no one knows anyone who lives on a farm that is sustainable without advanced technology and gasoline. And the way monoculture has taken over American farms, along with dependency on chemical fertilizers and insecticides, plus the lack of remotely enough dray beasts, classic farming can’t be rebuilt fast enough to service teeming millions.

And so teeming millions will die.

That’s not counting destruction and attrition from refugees from the cities. Refugees are not going to care where or how they get their food; they will take it if need be, over the dead bodies of whoever gets in the way. And they will vastly outnumber the local farmer folk and their local friends. It will be like that end scene in The Day After, when the refugees took the farmer’s cow and slaughtered it, and he went out to complain. He didn’t even threaten them, and they just mowed him down.

That will be played out over and over again, everywhere. 80% of Americans live in a city, which is a literal food wasteland. When they start moving out, it will be like locusts, and anyone who gets in their way simply dies.

Ian – all this assumes a hard collapse as opposed to a slow withering. But that scenario is entirely possibly with hard enough shocks, and we’re doing almost everything we can to ensure they happen.

 

You Can’t Make Good Decisions If You Believe Lies

Nate Wilcox recently wrote about the signal to noise ratio in the information we receive:

Coming in a context of other tweets about Germany’s up is down policies declaring Jews who oppose genocide in Palestine to be anti-semites, a nominally left wing publication disinforming their readers about Brazil’s Lula, relentless economic gaslighting, a seemingly cooked-up online conflict between Black Americans and Palestinians, and the MI6 blaming Russia for the UK’s recent racist pogroms…

Just before the Iraq war, 72% of Americans believed Iraq was behind 9/11. Official inflation numbers, as I’ve written often, complete fiction at this point. The propaganda around mass rape and beheading on Oct 7th has proven to have no physical evidence. Olds will remember the stories, in the original Gulf War, of how Iraq soldiers were bayoneting babies in hospitals. The NYTimes, also a prime purveyor of October 7 atrocity propaganda, systematically lied about Iraq WMD to justify the Iraq war. An academic study found that the British media lied about Corbyn around 80% of the time, and they managed to convince many Brits that the long time anti-racism protestor was anti-semitic. The WHO and the CDC denied that Covid was airborne for ages and pretended children weren’t particularly at risk.

And these are just highlights. One could make a list of thousands.

We are swimming in an ocean of shit.

No one can make good decisions: who to vote for, who to support, what to believe, or what to do, if they believe large numbers of lies.

And it truly is an Ocean of Shit: there’s so much that no one can keep up, certainly no one who doesn’t make it one of the main things they do.

Further, the lies send many people spiraling off into the worst kinds of conspiracy theories. “Conspiracy theory” isn’t a synonym for “wrong” there are plenty of real conspiracies (lately lots of them to raise prices, to pick a perfectly mundane one), but when you know you’re being lied to, and when it’s systematic, it’s hard to find a foundation point to build from, and from that to construct a relatively accurate model of reality.

If Corbyn’s an anti-semite, Putin loving, lying commie, perhaps you shouldn’t vote for him.

If Iraq was behind 9/11 then invading them makes sense.

And so on.

And this disease infects the professional and managerial classes the worst. Economists believe the figures coming out of the Bureau of Labor Statistics then propose or implement policies based on fictional numbers, for example.

Reality isn’t allowed to intrude until it’s beyond undeniable, at which point the major mistakes have already been made and the situation is often un-recoverable.

There’s more to it that this, of course. Almost everyone in our societies has been trained to be an order-taker, with lives that involve first doing what teacher says then doing what the boss says. Our ancestors called such people wage slaves and they were right. We’re also a consumer society: we pick from choices offered to us by others, we don’t produce our politics or our homes or our food or almost anything else: we don’t create and thus our choices are just from a menu offered by others.

People conditioned all their lives to do what they’re told, pick from a menu and swimming in an ocean of lies can’t make good decisions. It’s that simple.

The first step in fixing any problem is always facing and acknowledging the truth. If you can’t do that, all you can do is make another bad decision.


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Pavel Durov, CEO of Telegram, Arrested In France

Durov’s Russian, and an interesting guy. He refused to cooperate when Russia asked him for user information, for example. He appears to believe in the principle of freedom of speech, which is radical at this point. Telegram was banned in Russia from 2018 to 2021.

As most people know Telegram is where most uncensored information on the Russia-Ukraine and Gaza wars are to be found. Some of it, perhaps even a lot of it is bullshit, but if one really wants to know what’s happening, Telegram is one of the better places to find out, though it takes judgment and discretion. There are certainly Telegram channels which are far more accurate and honest than any major Western press outlet, just as there are those that are sewers of propaganda and lies.

France claims the arrest is because Telegram doesn’t moderate in line with EU law, which is probably true. The laws, however, are bad laws which make freedom of speech essentially impossible. The idea of misinformation has been weaponized to mean “what the government says is true” and since most governments are lying about both wars, well…

As Truman said, “I don’t give them Hell. I just tell the truth about them, and they think it’s Hell.”

Telegram is one of the few places left which somewhat lives up to the promise of the early internet of a place without censors or gatekeepers, where anyone could have their say. It’s understandable that governments and powerful people don’t want that, before the internet you could only be heard by large numbers of the gatekeepers would let you, and mostly they don’t. Youngs don’t remember that world, but it felt like there was constantly a gag on: there could be no honest speech which wasn’t approved.

There’s no sense in pretending it’s all upside, it isn’t, but the downsides are the price of actually allowing meaningful freedom of speech. In the old days we just didn’t hear from those the gatekeepers wouldn’t let thru. Oh, there were some exceptions, but they were exceptions.

So fuck France and fuck Macron. Just another fascist neoliberal who wants to remove freedoms and use them to enable war and genocide.

As for Pavel, he made a mistake traveling in Europe. It’s a hard balancing beam he’s on. Though Russia’s currently supportive, as Telegram is a way for their side to get their message out, they haven’t always been. There’s really no major free speech country left, and the fact is that even CEOs are at the mercy of states. You need a state to protect you, and there isn’t really a trustworthy one around any more.


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